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WHAT IS EMPLICITI?

EMPLICITI™ (elotuzumab) is a prescription medicine used to treat multiple myeloma in combination with the medicines REVLIMID® (lenalidomide) and dexamethasone in people who have received one to three prior treatments for their multiple myeloma.

It is not known if EMPLICITI is safe and effective in children.

 

image shows a woman who is an EMPLICITI patient, taking a selfie with two little girls
Angela B. • EMPLICITI patient What do EMPLICITI patients have to say?
 

Each of our patients has their own story to tell about their personal journey with multiple myeloma.

There's a story behind every selfie. Some EMPLICITI patients have shared their personal stories to help encourage others fighting multiple myeloma. Each picture reflects a memory they've shared with the important people who bring hope and joy to their lives.

Click below to hear from real EMPLICITI patients and their loved ones.

Rick's Story ∙ EMPLICITI patient

I grew up with a big backyard and so I was always off having adventures outside. When things get tough, the woods have always been there for me. Fishing, being outside and enjoying nature—all of those things are like therapy for me. I think my family, faith, and nature are the most important things in life, so I don’t sweat the small stuff. No matter what you can't quit. You have to keep up the fight. I know that whatever happens next, I will keep fighting. Nothing is worth giving up.

Denise's Story ∙ EMPLICITI caregiver

Being a caregiver feels like I’m going through everything, too. I just jump right in and don’t give up. You have to just be strong and keep the faith. We’re going to get through this, and even if you don’t believe it, you’ve got to act like you do. I do believe it though.

Angela's Story ∙ EMPLICITI patient

I get along great with the doctors and the nurses. The nurses I see regularly are so supportive. They talk to me about their families, how their new babies are doing, their kids... and whenever I see one of my doctors she always gives me the thumbs up. I respect them, I think they're great, I think they're brilliant, and I feel like my clinic is nearly a home away from home. I couldn’t ask for a better team of nurses and doctors.

My best friend Wade really helped me through my diagnosis and treatment. He supports me and makes me laugh along the way. We talk and laugh, even when we are sitting in the waiting room for my treatments. We have a good time together as friends. That’s always been our normal routine, so that’s what makes me feel the most comfortable through it all. I don’t know what I’d have done without having Wade by my side.

Wade's Story ∙ EMPLICITI caregiver

I believe it’s my job to hold her up whenever she needs me to. She’s done the same for me for years, so it was just something I did without even thinking about it.

Would You Like to Share Your Story?

If you or a loved one is interested in sharing your
experience on treatment, call 1-800-481-8753

Selected Important Facts About EMPLICITI

Liver problems may occur in patients who receive EMPLICITI. Symptoms of liver problems include:

  • tiredness
  • weakness
  • loss of appetite
  • yellowing of your skin or eyes
  • color changes in your stools
  •  
  • confusion
  • swelling of the stomach area

Your healthcare provider will do blood tests to check your liver function during your treatment with EMPLICITI.

Talk to your healthcare team if you have any of the signs and symptoms of liver problems.

Please read Important Facts below, including other serious side effects.

Call 1-844-EMPLICITI (1-844-367-5424)
am to 8 pm ET Monday through Friday

Or call your doctor
Get Started on EMPLICITI

Important Facts About EMPLICITI™ (elotuzumab)OTHER IMPORTANT FACTS

EMPLICITI in combination with REVLIMID® (lenalidomide) and dexamethasone may cause the following serious side effects: Infusion reactions, infections, risk of developing new cancers (malignancies), and liver problems. There are also other serious risks associated with REVLIMID to females and males of reproductive potential, including possible serious birth defects or death of an unborn baby, and specific requirements regarding birth control, pregnancy testing and blood and/or sperm donation. For more information, please read the Important Facts throughout this website or by expanding this section. Your healthcare team will work with you to manage any side effects you may experience throughout your treatment with EMPLICITI.

This is a summary of important information that you need to know about EMPLICITI. Your healthcare team can work with you to help answer any questions you may have about EMPLICITI.

Keep this information in a safe place, so you can refer to it before and during your treatment. Look out for these icons as you read:

Talk to your healthcare teamCall a healthcare provider right awayHelpful information to remember
What is EMPLICITI?

EMPLICITI is a prescription medicine used to treat multiple myeloma in combination with other medications:

EMPLICITI
(elotuzumab)
  REVLIMID®
(lenalidomide)
  dexamethasone

Remember to read the safety information for the other medications you are receiving.

EMPLICITI is for patients who have received one to three prior treatments for their multiple myeloma.

EMPLICITI is for adults. The safety and effectiveness of EMPLICITI has not been studied in children.

What are the possible side effects of EMPLICITI?

EMPLICITI may cause side effects, some of which can be serious. Your healthcare team will work with you to manage any side effects you may experience throughout your treatment with EMPLICITI.

Serious side effects

Infusion reactions can happen during your EMPLICITI infusion or within 24 hours after your infusion.
Symptoms of an infusion reaction may include:

  • fever
  • chills
  • rash
  • trouble breathing
  • dizziness
  • light-headedness

Before every EMPLICITI infusion, your healthcare team will give you medications to help reduce the risk of infusion reactions.
If you have an infusion reaction while receiving EMPLICITI, your healthcare provider will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction your healthcare provider may stop your treatment completely.

Call your healthcare provider or get medical help right away if you have any of the above symptoms after your infusion with EMPLICITI.

Infections may develop in patients who receive EMPLICITI with REVLIMID and dexamethasone, and can be serious. Symptoms of an infection may include:

  • fever
  • flu-like symptoms
  • cough
  • shortness of breath
  • burning with urination
  • painful skin rash

Call a healthcare provider right away if you have any of the signs and symptoms of an infection.

Developing new cancers (malignancies) is a risk in patients who receive EMPLICITI with REVLIMID and dexamethasone. Your healthcare provider will check you for new cancers during your treatment with EMPLICITI.

Talk to your healthcare team to learn more about your risk of developing new cancers if you receive EMPLICITI with REVLIMID and dexamethasone.

Liver problems may occur in patients who receive EMPLICITI. Symptoms of liver problems include:

  • tiredness
  • weakness
  • loss of appetite
  • yellowing of your skin or eyes
  • color changes in your stools
  •  
  • confusion
  • swelling of the stomach area

Your healthcare provider will do blood tests to check your liver function during your treatment with EMPLICITI.

Talk to your healthcare team if you have any of the signs and symptoms of liver problems.

The most common side effects

  • fatigue
  • diarrhea
  • fever
  • constipation
  • cough
  • numbness, weakness, tingling, or burning pain in your arms or legs
  • sore throat or runny nose
  • upper respiratory tract infection
  • decreased appetite
  • pneumonia

These are not all of the possible side effects of EMPLICITI.

Call your doctor for medical advice about side effects.

You can report any side effects you experience to the FDA by calling 1-800-FDA-1088.

What should I discuss with my healthcare team before starting EMPLICITI?

Talk to your healthcare team about all of your medical conditions, including if you have an infection.

Let your healthcare team know as soon as possible if you are a woman who is pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed. It is not known if EMPLICITI can harm an unborn baby. However, REVLIMID®  may cause birth defects or death of an unborn baby. It is not known if EMPLICITI passes into breastmilk. You should not breastfeed during treatment with EMPLICITI with REVLIMID and dexamethasone.

Before receiving EMPLICITI with REVLIMID and dexamethasone females and males must agree to the instructions in the REVLIMID REMS® program. The REVLIMID REMS program has specific requirements about birth control (contraception), pregnancy testing, blood donation, and sperm donation that you need to know.

Talk to your healthcare team to learn more about REVLIMID.

Interactions with other drugs may affect the way EMPLICITI works in your body.

Talk to your healthcare team about all of the medicines you are taking before starting EMPLICITI, including:

  • prescription medicines
  • over-the-counter medicines
  • vitamins
  • herbal supplements

Please read Patient Information in the Full Prescribing Information.

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