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WHAT IS EMPLICITI?

EMPLICITI™ (elotuzumab) is a prescription medicine used to treat multiple myeloma in combination with the medicines REVLIMID® (lenalidomide) and dexamethasone in people who have received one to three prior treatments for their multiple myeloma.

It is not known if EMPLICITI is safe and effective in children.

 

 image shows a portrait of a woman identified as Debra M., with a man and pet dog.
Debra M.Where do I go for multiple myeloma support?
 

Bristol-Myers Squibb is committed to helping patients throughout their treatment with EMPLICITI™ (elotuzumab). You can expect an ongoing commitment to providing you with information, education and multiple myeloma support resources.

What is Multiple Myeloma?

Multiple myeloma is the second most common type of blood cancer. It forms in a type of white blood cell called a plasma cell. Plasma cells are part of the immune system and help fight infections. With multiple myeloma, plasma cells become cancerous and accumulate in the bone marrow, where they crowd out healthy blood cells. The cancerous cells produce abnormal proteins (M protein). This disease damages the bones, immune system and kidneys. Although multiple myeloma is not currently curable, it is considered a treatable disease thanks to currently available treatment options.

Scroll for more multiple myeloma resources and links to helpful organizations.

Questions to
Ask Your Doctor

This guide includes questions you may want to ask your oncologist about EMPLICITI.

EMPLICITI
Treatment Guide

This brochure explains treatment with EMPLICITI and how it may
help you.

EMPLICITI
Treatment Calendar

Track your treatments efficiently with this convenient calendar.

EMPLICITI
Caregiver Brochure

This brochure explains treatment with EMPLICITI and how it may help your loved one.

 

Other Patient Resources

You may be able to find help arranging transportation to and from medical appointments. Please contact the organizations listed below for more information about programs in your area and to find out if you are eligible for their services.

Multiple myeloma support resources:

CLICK THE ORGANIZATION'S LOGO BELOW TO LEARN MORE.

Please remember that the first and best resource for any questions or concerns you may have about living with multiple myeloma is your healthcare team. Bristol-Myers Squibb is not affiliated with nor endorses these organizations, and the contact information above does not suggest endorsement.

Real Patients
Every patient has a story to share. Click to read more about real EMPLICITI patients and their journey with multiple myeloma
Call 1-844-EMPLICITI (1-844-367-5424)
am to 8 pm ET Monday through Friday

Or call your doctor
EMPLICITI With You

Sign up now for complimentary support, tools, and educational resources

SIGN UP NOW

Important Facts About EMPLICITI™ (elotuzumab)OTHER IMPORTANT FACTS

EMPLICITI in combination with REVLIMID® (lenalidomide) and dexamethasone may cause the following serious side effects: Infusion reactions, infections, risk of developing new cancers (malignancies), and liver problems. There are also other serious risks associated with REVLIMID to females and males of reproductive potential, including possible serious birth defects or death of an unborn baby, and specific requirements regarding birth control, pregnancy testing and blood and/or sperm donation. For more information, please read the Important Facts throughout this website or by expanding this section. Your healthcare team will work with you to manage any side effects you may experience throughout your treatment with EMPLICITI.

This is a summary of important information that you need to know about EMPLICITI. Your healthcare team can work with you to help answer any questions you may have about EMPLICITI.

Keep this information in a safe place, so you can refer to it before and during your treatment. Look out for these icons as you read:

Talk to your healthcare teamCall a healthcare provider right awayHelpful information to remember
What is EMPLICITI?

EMPLICITI is a prescription medicine used to treat multiple myeloma in combination with other medications:

EMPLICITI
(elotuzumab)
  REVLIMID®
(lenalidomide)
  dexamethasone

Remember to read the safety information for the other medications you are receiving.

EMPLICITI is for patients who have received one to three prior treatments for their multiple myeloma.

EMPLICITI is for adults. The safety and effectiveness of EMPLICITI has not been studied in children.

What are the possible side effects of EMPLICITI?

EMPLICITI may cause side effects, some of which can be serious. Your healthcare team will work with you to manage any side effects you may experience throughout your treatment with EMPLICITI.

Serious side effects

Infusion reactions can happen during your EMPLICITI infusion or within 24 hours after your infusion.
Symptoms of an infusion reaction may include:

  • fever
  • chills
  • rash
  • trouble breathing
  • dizziness
  • light-headedness

Before every EMPLICITI infusion, your healthcare team will give you medications to help reduce the risk of infusion reactions.
If you have an infusion reaction while receiving EMPLICITI, your healthcare provider will slow or stop your infusion and treat your reaction. If you have a severe infusion reaction your healthcare provider may stop your treatment completely.

Call your healthcare provider or get medical help right away if you have any of the above symptoms after your infusion with EMPLICITI.

Infections may develop in patients who receive EMPLICITI with REVLIMID and dexamethasone, and can be serious. Symptoms of an infection may include:

  • fever
  • flu-like symptoms
  • cough
  • shortness of breath
  • burning with urination
  • painful skin rash

Call a healthcare provider right away if you have any of the signs and symptoms of an infection.

Developing new cancers (malignancies) is a risk in patients who receive EMPLICITI with REVLIMID and dexamethasone. Your healthcare provider will check you for new cancers during your treatment with EMPLICITI.

Talk to your healthcare team to learn more about your risk of developing new cancers if you receive EMPLICITI with REVLIMID and dexamethasone.

Liver problems may occur in patients who receive EMPLICITI. Symptoms of liver problems include:

  • tiredness
  • weakness
  • loss of appetite
  • yellowing of your skin or eyes
  • color changes in your stools
  •  
  • confusion
  • swelling of the stomach area

Your healthcare provider will do blood tests to check your liver function during your treatment with EMPLICITI.

Talk to your healthcare team if you have any of the signs and symptoms of liver problems.

The most common side effects

  • fatigue
  • diarrhea
  • fever
  • constipation
  • cough
  • numbness, weakness, tingling, or burning pain in your arms or legs
  • sore throat or runny nose
  • upper respiratory tract infection
  • decreased appetite
  • pneumonia

These are not all of the possible side effects of EMPLICITI.

Call your doctor for medical advice about side effects.

You can report any side effects you experience to the FDA by calling 1-800-FDA-1088.

What should I discuss with my healthcare team before starting EMPLICITI?

Talk to your healthcare team about all of your medical conditions, including if you have an infection.

Let your healthcare team know as soon as possible if you are a woman who is pregnant, planning to become pregnant, breastfeeding, or planning to breastfeed. It is not known if EMPLICITI can harm an unborn baby. However, REVLIMID®  may cause birth defects or death of an unborn baby. It is not known if EMPLICITI passes into breastmilk. You should not breastfeed during treatment with EMPLICITI with REVLIMID and dexamethasone.

Before receiving EMPLICITI with REVLIMID and dexamethasone females and males must agree to the instructions in the REVLIMID REMS® program. The REVLIMID REMS program has specific requirements about birth control (contraception), pregnancy testing, blood donation, and sperm donation that you need to know.

Talk to your healthcare team to learn more about REVLIMID.

Interactions with other drugs may affect the way EMPLICITI works in your body.

Talk to your healthcare team about all of the medicines you are taking before starting EMPLICITI, including:

  • prescription medicines
  • over-the-counter medicines
  • vitamins
  • herbal supplements

Please read Patient Information in the Full Prescribing Information.

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